Cavaliers vs. Celtics Prediction, Odds, Picks – Oct. 29

The Cleveland Cavaliers (3-1) will attempt to extend a three-game winning stretch when visiting the Boston Celtics (1-3) on October 29, 2025 at TD Garden. Wednesday’s game between the Cavaliers and the Celtics sees the Cavaliers as 4.5-point favorites. The over/under is 232.5 points for the game.

Take a look at everything you need to know about the Cavaliers-Celtics game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Cavaliers vs. Celtics Game Information, TV Channel & Odds

• When: Wednesday, October 29, 2025 at 7 p.m. ET
• Where: TD Garden in Boston, Massachusetts
• TV: ESPN, NBCS-BOS, and FDSOH
• Live Boxscore: FOX Sports

Cavaliers vs. Celtics Prediction

ATS Pick: Celtics (+ 4.5)
O/U Pick: Under (232.5)
Score Prediction: Cavaliers 115 – Celtics 111

Cavaliers vs. Celtics Betting Insights

• The Cavaliers’ 82 games last season went over this contest’s total of 232.5 points 44 times.
• The Celtics played 24 games last season that ended with a combined score higher than 232.5 points.
• The two teams combined to score 238.2 points per game last season, 5.7 more points than this matchup’s total.
• Combined, these teams allowed 219.6 points per contest last year, 12.9 fewer points than the total for this game.
• Cavaliers outings last season had an average point total of 231, 1.5 more points than this game’s over/under.
• The average over/under for Celtics outings last year was 226.3, 6.2 fewer points than this game’s point total.

Cavaliers Recent Trends

• Cleveland covered 47 times in 82 matchups with a spread last season.
• Cleveland covered the spread 33 times last season (33-26-2 ATS) when playing as at least a 4.5-point favorite.
• A total of 50 Cleveland games last season banger the over.
• Last year, the 121.9 points per game the Cavaliers put up were 14.7 more points than the Celtics allowed (107.2).
• Cleveland had a 47-28-2 record against the spread and a 63-14 record overall last season when scoring more than 107.2 points.
• The Cavaliers shot 49.1% from the field last season, 4.1 percentage points higher than the 45% the Celtics allowed to opponents.
• The Cavaliers sported a worse record against the spread in home games (23-17-1) than they did in road games (24-16-1) last season.
• Cleveland eclipsed the over/under in the same percentage of home games as road tilts (61%) last year.
• As a moneyline favorite last season, the Cavaliers picked up the win in 34 of 40 games when playing at home, good for a .850 winning percentage. They won 26 of 34 games away from home (.765) as a moneyline favorite.

Cavaliers Recent Stats

Cavaliers Leaders

• Donovan Mitchell recorded 24 points last year, plus 4.5 boards and 5 assists.
• Last season, Evan Mobley recorded an average of 18.5 points, 9.3 rebounds and 3.2 assists per game.
• Darius Garland recorded 20.6 points, 2.9 rebounds and 6.7 assists per contest, plus 1.2 steals and 0.1 blocks.
• Jarrett Allen’s numbers last season were 13.5 points, 9.7 rebounds and 1.9 assists per game. He made 70.6% of his shots from the floor (first in league).
• De’Andre Hunter’s numbers last season were 17 points, 4 rebounds and 1.4 assists per game. He drained 47% of his shots from the floor and 40.5% from beyond the arc, with an average of 2.5 triples.

Celtics Recent Trends

• The Celtics went 39-42-1 ATS last season.
• Boston won once ATS (1-1) as an underdog of 4.5 points or greater last year.
• A total of 37 of the Celtics’ games last season banger the over.
• The Celtics’ 116.3 points per game last year were just 3.9 more points than the 112.4 the Cavaliers gave up.
• Boston went 32-21-1 against the spread and 46-8 overall when it scored more than 112.4 points last season.
• The Celtics shot 46.2% from the field, 0.8% higher than the 45.4% the Cavaliers’ opponents shot last season.
• Last season, the Celtics were 18-23-0 at home against the spread (.439 winning percentage). On the road, they were 21-19-1 ATS (.512).
• Looking at the over/under, Boston’s games went over more frequently at home (21 of 41, 51.2%) than away (16 of 41, 39%) last season.
• The Celtics’ winning percentage at home when moneyline favorites was .675 (27-13) last season, and on the road it was .842 (32-6).

Celtics Recent Stats

Celtics Leaders

• Jayson Tatum put up 26.8 points, 8.7 boards and 6 assists per game last season.
• Derrick White made 3.5 threes per game a season ago.
• Tatum averaged 1.1 takeaways per game, while White compiled 1.1 rejections per contest.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.